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Pyrimethanil

Katalog-Nr.GC61755 Copy One-Click Copy Product Info

Pyrimethanil ist ein Anilinopyrimidin und ein Breitspektrum-Kontaktfungizid zur BekÄmpfung von Botrytis spp.

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Pyrimethanil Chemische Struktur

Cas No.: 53112-28-0

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10mM (in 1mL DMSO)
52,00 $
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50 mg
46,00 $
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Sample solution is provided at 25 µL, 10mM.



Description of Pyrimethanil

Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].

Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil (5 and 50 µg/L) elicits a range of toxic responses, has the potential to induce histological alterations in tissues of the Italian tree frog H. intermedia after a long term exposure to two environmentally relevant concentrations of Pyrimethanil[2].Pyrimethanil decreases polygalacturonase, cellulase, proteinase and laccase activities in the medium of three day‐old cultures. The pyrimethanil results in 50% reduction (IC50) in total enzyme activities are approximately 0.25 μM for polygalacturonase, cellulase and proteinase, and approximately 1.0 μM for laccase[3].

[1]. Petr Masner, et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pesticide Science [2]. L Kanetis, et al. Characterization of genetic and biochemical mechanisms of fludioxonil and pyrimethanil resistance in field isolates of Penicillium digitatum. Phytopathology [3]. Richard J. Milling, et al. Mode of action of the anilino‐pyrimidine fungicide pyrimethanil. 2. Effects on enzyme secretion in Botrytis cinerea. Volume45, Issue1, September 1995. [4]. Salvatore D'Aquino, et al. Residue levels and effectiveness of pyrimethanil vs imazalil when using heated postharvest dip treatments for control of Penicillium decay on citrus fruit. J Agric Food Chem. 2006 Jun 28;54(13):4721-6.

Chemical Properties of Pyrimethanil

Cas No. 53112-28-0 SDF
Canonical SMILES CC1=CC(C)=NC(NC2=CC=CC=C2)=N1
Formula C12H13N3 M.Wt 199.25
Löslichkeit DMSO: 130 mg/mL (652.45 mM) Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Pyrimethanil

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1 mg 5 mg 10 mg
1 mM 5.0188 mL 25.0941 mL 50.1882 mL
5 mM 1.0038 mL 5.0188 mL 10.0376 mL
10 mM 501.9 μL 2.5094 mL 5.0188 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 3 reference(s) in Google Scholar.)

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