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(Rac)-Lys-SMCC-DM1 (Synonyms: (Rac)-Lys-Nε-MCC-DM1)

Katalog-Nr.GC64069

(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) ist das Racemat von Lys-SMCC-DM1. Lys-SMCC-DM1 ist eine Linker-Payload-Komponente, die das Potenzial hat, die Tubulin-Polymerisation zu hemmen. Lys-SMCC-DM1 ist der aktive Metabolit von T-DM1.

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(Rac)-Lys-SMCC-DM1 Chemische Struktur

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1 mg
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5 mg
855,00 $
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10 mg
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 . Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1[1].

[1]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

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