Retreversine |
| Katalog-Nr.GC41468 |
Retreversine ist eine inaktive Kontrolle fÜr Reversine. Reversin ist eine neue Klasse von ATP-kompetitiven Aurora-Kinase-Inhibitoren.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1028332-91-3
Sample solution is provided at 25 µL, 10mM.
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Terminal differentiation of embryonic progenitor cells to form distinct, adult tissues is the hallmark of organogenesis in complex organisms. However, in mammals including humans, this process is not readily reversible. Reversine is a 2,6-disubstituted purine derivative that was identified using a screening system based on the loss of terminal differentiation markers in C2C12 myoblast cells. Retreversine is an inactive control molecule, created by simply interchanging the 2 and 6-substituents on the purine ring. Retreversine is inactive at 10-fold higher concentrations than reversine in the myoblast assay.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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