Ribostamycin Sulfate |
| Katalog-Nr.GC16370 |
Ribostamycinsulfat (Vistamycinsulfat) ist ein antimikrobielles Breitbandmittel, hemmt die bakterielle Proteinsynthese auf der Ebene der 30S- und 50S-Bindung der ribosomalen Untereinheit und hemmt auch die ChaperonaktivitÄt der Proteindisulfidisomerase (PDI), die in pharmakokinetischen und NephrotoxizitÄtsstudien verwendet wird
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 53797-35-6
Sample solution is provided at 25 µL, 10mM.
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Ribostamycin is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies
References:
[1]. Baud H, et al. Ribostamycin, as an intermediate in the biosynthesis of neomycin. J Antibiot (Tokyo). 1977 Sep;30(9):720-3.
[2]. Hunfeld KP, et al. In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi. Int J Antimicrob Agents. 2001 Mar;17(3):203-8.
[3]. Horibe T, et al. Ribostamycin inhibits the chaperone activity of protein disulfide isomerase. Biochem Biophys Res Commun. 2001 Dec 21;289(5):967-72.
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