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Salvinorin A Propionate (Synonyms: Salvinorinyl-2-propionate)

Katalog-Nr.GC44870

Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM.

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Salvinorin A Propionate Chemische Struktur

Cas No.: 689295-71-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over µ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 µg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A .

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