Secretin (human) (trifluoroacetate salt) |
| Katalog-Nr.GC44881 |
Secretin is an endogenous 27-amino acid gastrointestinal hormone and neuropeptide that regulates secretion from the stomach, pancreas, and liver.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Secretin is an endogenous 27-amino acid gastrointestinal hormone and neuropeptide that regulates secretion from the stomach, pancreas, and liver. It belongs to the secretin/glucagon superfamily of peptides, which includes glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . Secretin dose-dependently increases somatostatin release from primary human antral cells in vitro. In vivo, secretin dose-dependently increases the volume of pancreatic secretion as well as inhibits gastric acid secretion induced by gastrin I in rats when administered at a dose of 100 pmol/kg per h. Secretin (40 μg/kg, i.v.) increases the number of neurons expressing c-fos in the central amygdala and area postrema in rats.
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