Thalidomide 4'-ether-alkylC6-amine |
| Katalog-Nr.GC50528 |
Thalidomide 4'-ether-alkylC6-amine ist ein synthetisiertes E3-Ligase-Ligand-Linker-Konjugat, das in PROTAC dTAG-13, einem Abbauer von FKBP12F36V und BET, verwendet wird.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-88-3
Sample solution is provided at 25 µL, 10mM.
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Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a C6 alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTACs R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 4 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Nabet et al (2018) The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 14 431 PMID:29581585 |Erb et al (2017) Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 543 270 PMID:28241139
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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