UNC6852 |
| Katalog-Nr.GC39588 |
UNC6852 ist ein selektiver Polycomb Repressive Complex 2 (PRC2)-Degrader auf der Basis von PROTAC und enthÄlt einen EED-Liganden (embryonale Ektodermentwicklung) und einen von Hippel-Lindau-Liganden mit einem IC50-Wert von 247 nM fÜr EED.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2688842-08-0
Sample solution is provided at 25 µL, 10mM.
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UNC6852 is a selective rolycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand, with an IC50 of 247 nM for EED[1].
[1]. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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