Withanolide A (Synonyms: Withaniol, WL-A) |
Katalog-Nr.GC41624 |
Withanolid A, isoliert aus der indischen pflanzlichen Droge Ashwagandha (Wurzel von Withania somnifera), konnte Neuriten regenerieren und Synapsen in schwer geschÄdigten Neuronen rekonstruieren.
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Cas No.: 32911-62-9
Sample solution is provided at 25 µL, 10mM.
Withanolide A is a natural product isolated from the medicinal plant W. somnifera that has antioxidant and neuroprotective activity. It helps to promote neurite outgrowth at 1 µM in cultured neurons and in rodents injected with Aβ(25-35), and also recovers Aβ(25-35)-induced memory deficit in mice (10 µmol/kg/day). Withanolide A reverses hypoxia-mediated neurodegeneration by restoring hypoxia-induced glutathione depletion in the hippocampus of mice.
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