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Home >> Signaling Pathways >> Cardiovascular

Cardiovascular

Cardiovascular

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.

Targets for  Cardiovascular

Products for  Cardiovascular

  1. Cat.No. Product Name Information
  2. GC52035 Esmolol Acid (hydrochloride) An active metabolite of esmolol Esmolol Acid (hydrochloride) Chemical Structure
  3. GC47307 Esmolol-d7 (hydrochloride) An internal standard for the quantification of esmolol Esmolol-d7 (hydrochloride) Chemical Structure
  4. GC33760 ETC-1002 (ESP-55016) ETC-1002 (ESP-55016) (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor. ETC-1002 (ESP-55016) Chemical Structure
  5. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  6. GC48916 Etilefrine (hydrochloride) A sympathomimetic amine Etilefrine (hydrochloride) Chemical Structure
  7. GC49762 Etiocholanedione A neurosteroid Etiocholanedione Chemical Structure
  8. GC32451 Examorelin (Hexarelin) A peptide agonist of GHS-R Examorelin (Hexarelin) Chemical Structure
  9. GC43646 Ezetimibe Hydroxy Glucuronide Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe . Ezetimibe Hydroxy Glucuronide Chemical Structure
  10. GC49230 Ferroprotoporphyrin Ferroprotoporphyrin, a complex of ferrous iron and a porphyrin, is an isosteric inhibitor of fatty acid binding to rat liver fatty acid binding protein. Ferroprotoporphyrin Chemical Structure
  11. GC49518 Fluindione A vitamin K antagonist Fluindione Chemical Structure
  12. GC45761 Flupirtine-d4 (hydrochloride) An internal standard for the quantification of flupirtine Flupirtine-d4 (hydrochloride) Chemical Structure
  13. GC47367 Fluvastatin (sodium salt hydrate) An HMG-CoA reductase inhibitor Fluvastatin (sodium salt hydrate) Chemical Structure
  14. GC47371 Fosinopril-d7 (sodium salt) An internal standard for the quantification of fosinopril Fosinopril-d7 (sodium salt) Chemical Structure
  15. GC49089 FR900359

    A cyclic depsipeptide and an inhibitor of Gαq, Gα11, and Gα14

     FR900359 Chemical Structure
  16. GC18260 FTase Inhibitor I FTase inhibitor I is a potent inhibitor of farnesyltransferase (FTase; IC50 = 21 nM) that is greater than 30-fold selective for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). FTase Inhibitor I Chemical Structure
  17. GC47385 Furosemide-d5 An internal standard for the quantification of furosemide Furosemide-d5 Chemical Structure
  18. GC47387 G6PDi-1 An inhibitor of G6PDH G6PDi-1 Chemical Structure
  19. GC43727 Ganglioside GD1a mixture (sodium salt)

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

     Ganglioside GD1a mixture (sodium salt) Chemical Structure
  20. GC43732 Ganglioside GM3 Mixture (sodium salt) Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. Ganglioside GM3 Mixture (sodium salt) Chemical Structure
  21. GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities Ganoderic Acid DM Chemical Structure
  22. GP10107 Gap 26 Gap 26 Chemical Structure
  23. GP10119 Gap 27

    A connexin-mimetic peptide

     Gap 27 Chemical Structure
  24. GC49416 Gap 27 (trifluoroacetate salt) A connexin-mimetic peptide Gap 27 (trifluoroacetate salt) Chemical Structure
  25. GC47397 Gemfibrozil-d6 An internal standard for the quantification of gemfibrozil Gemfibrozil-d6 Chemical Structure
  26. GC43745 Geranyl Pyrophosphate (triammonium salt) Geranyl Pyrophosphate (triammonium salt) is a key intermediate in the isoprenoid biosynthesis pathway (IBP). Geranyl Pyrophosphate (triammonium salt) Chemical Structure
  27. GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide Gliclazide-d4 Chemical Structure
  28. GC47413 Glycoursodeoxycholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Glycoursodeoxycholic Acid-d4 Chemical Structure
  29. GC49509 Glycyl-L-Glutamine (hydrate) A dipeptide fragment of β-endorphin Glycyl-L-Glutamine (hydrate) Chemical Structure
  30. GC18788 Graphislactone A Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. Graphislactone A Chemical Structure
  31. GP10115 GTP-Binding Protein Fragment, G alpha GTP-Binding Protein Fragment, G alpha Chemical Structure
  32. GC49117 Guanadrel An antihypertensive agent Guanadrel Chemical Structure
  33. GC47416 Guanfacine-13C,15N3 An internal standard for the quantification of guanfacine Guanfacine-13C,15N3 Chemical Structure
  34. GC45678 Guanoclor A guanidinium antihypertensive Guanoclor Chemical Structure
  35. GC43800 GW 9578 Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor found predominantly in the liver that is involved in the regulation of lipid homeostasis. GW 9578 Chemical Structure
  36. GC49255 GYKI 52466 (hydrochloride) An allosteric AMPA receptor antagonist GYKI 52466 (hydrochloride) Chemical Structure
  37. GC47418 Gymnoascolide A A fungal metabolite with fungicidal and vasodilatory activities Gymnoascolide A Chemical Structure
  38. GC49305 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt) An RGD-containing tetrapeptide H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt) Chemical Structure
  39. GC43802 HA-1004 (hydrochloride) HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively). HA-1004 (hydrochloride) Chemical Structure
  40. GC43803 HA-1077 (hydrochloride) Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. HA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator. HA-1077 (hydrochloride) Chemical Structure
  41. GC49882 Hemokinin 1 (human) (trifluoroacetate salt) A peptide agonist of NK1 receptors Hemokinin 1 (human) (trifluoroacetate salt) Chemical Structure
  42. GP10040 heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

    Thrombin inhibitor

     heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] Chemical Structure
  43. GP10027 heparin cofactor II precursor fragment [Homo sapiens]

    Thrombin inhibitor

     heparin cofactor II precursor fragment [Homo sapiens] Chemical Structure
  44. GC49543 Hepcidin-25 (trifluoroacetate salt) A peptide hormone Hepcidin-25 (trifluoroacetate salt) Chemical Structure
  45. GC47423 Heptaminol An aliphatic amine with cardiotonic and sympathomimetic activities Heptaminol Chemical Structure
  46. GC45469 Hexacosanoic Acid-d4   Hexacosanoic Acid-d4 Chemical Structure
  47. GC49091 Hirudin (54-65; non-sulfated) (trifluoroacetate salt) A desulfated peptide fragment of hirudin Hirudin (54-65; non-sulfated) (trifluoroacetate salt) Chemical Structure
  48. GC48897 Homocarnosine Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine Chemical Structure
  49. GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline Homocitrulline-d3 Chemical Structure
  50. GC43869 Homovanillic Acid sulfate (sodium salt) Homovanillic acid sulfate is a phenol found in olive oil and a dopamine metabolite. Homovanillic Acid sulfate (sodium salt) Chemical Structure
  51. GC47440 Hydrocortisone-d4 An internal standard for the quantification of hydrocortisone Hydrocortisone-d4 Chemical Structure
  52. GC47441 Hydroflumethiazide-13C-d2 An internal standard for the quantification of hydroflumethiazide Hydroflumethiazide-13C-d2 Chemical Structure
  53. GC49250 Hydroxydehydro Nifedipine Carboxylate A metabolite of nifedipine Hydroxydehydro Nifedipine Carboxylate Chemical Structure
  54. GC43883 Hymeglusin

    Hymeglusin is a fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme.

     Hymeglusin Chemical Structure
  55. GC17816 I-BOP TP specific agonist I-BOP Chemical Structure
  56. GC43910 I-SAP I-SAP is a high affinity TP receptor antagonist. I-SAP Chemical Structure
  57. GC43890 ICI 216140 Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. ICI 216140 Chemical Structure
  58. GC40485 Icosabutate Icosabutate is a synthetic ω-3 polyunsaturated fatty acid derived from eicosapentaenoic alcohol and 2-bromo butyric acid. Icosabutate Chemical Structure
  59. GC49195 Indapamide-13C-d3 An internal standard for the quantification of indapamide Indapamide-13C-d3 Chemical Structure
  60. GC48621 INNO-8875 INNO-8875 (INO-8875), an adenosine mimetic, is a highly selective Adenosine A1 receptor agonist. INNO-8875 Chemical Structure
  61. GC45728 Iohexol-d5 An internal standard for the quantification of iohexol Iohexol-d5 Chemical Structure
  62. GC49493 IRL 1620 (trifluoroacetate salt) A peptide ETB receptor agonist IRL 1620 (trifluoroacetate salt) Chemical Structure
  63. GC49634 Isoflupredone Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone Chemical Structure
  64. GC49343 Isoproterenol-d7 (hydrochloride) An internal standard for the quantification of isoproterenol Isoproterenol-d7 (hydrochloride) Chemical Structure
  65. GC47479 JP-1302 (hydrochloride hydrate) An α2C-adrenergic receptor antagonist JP-1302 (hydrochloride hydrate) Chemical Structure
  66. GC48432 KB-130015 An antiarrhythmic agent KB-130015 Chemical Structure
  67. GC43997 KDdiA-PC Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. KDdiA-PC Chemical Structure
  68. GC44011 KOdiA-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. KOdiA-PC Chemical Structure
  69. GC44013 KR-32568 KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). KR-32568 Chemical Structure
  70. GC47532 KUS121 A VCP modulator KUS121 Chemical Structure
  71. GC49436 L-3-n-Butylphthalide A phthalide with antiplatelet and neuroprotective activities L-3-n-Butylphthalide Chemical Structure
  72. GC52310 L-Arginine-13C6 (hydrochloride) An internal standard for the quantification of L-arginine L-Arginine-13C6 (hydrochloride) Chemical Structure
  73. GC49374 L-Arginine-d7 (hydrochloride) An internal standard for the quantification of L-arginine L-Arginine-d7 (hydrochloride) Chemical Structure
  74. GC47563 L-Glutamic Acid (ammonium salt) An excitatory neurotransmitter L-Glutamic Acid (ammonium salt) Chemical Structure
  75. GC49377 L-Glutamine-d5 An internal standard for the quantification of L-glutamine L-Glutamine-d5 Chemical Structure
  76. GC44062 L-hydroxy Arginine (acetate) L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. L-hydroxy Arginine (acetate) Chemical Structure
  77. GC48937 L-Tyrosine-13C9,15N An internal standard for the quantification of L-tyrosine L-Tyrosine-13C9,15N Chemical Structure
  78. GC52497 Lactosylceramide (porcine RBC) A sphingolipid Lactosylceramide (porcine RBC) Chemical Structure
  79. GC40142 Lactosylceramides (bovine buttermilk) Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid. Lactosylceramides (bovine buttermilk) Chemical Structure
  80. GC40807 Levonordefrin Levonordefrin is the (-)-enantiomer of nordefrin, a synthetic derivative of norepinephrine, that acts as a vasoconstrictor. Levonordefrin Chemical Structure
  81. GC40239 Limaprost-d3 Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS. Limaprost-d3 Chemical Structure
  82. GC49738 Lipid 29 An ionizable amino lipid Lipid 29 Chemical Structure
  83. GC45501 Lisinopril-d5   Lisinopril-d5 Chemical Structure
  84. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  85. GC44093 Lutein Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina. Lutein Chemical Structure
  86. GC41452 Luteoloside Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. Luteoloside Chemical Structure
  87. GC49916 Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) A bradykinin B1 receptor antagonist Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) Chemical Structure
  88. GC47587 Lyso-PAF C-16-d4 An internal standard for the quantification of LysoPAF C16 Lyso-PAF C-16-d4 Chemical Structure
  89. GC18241 Lysophosphatidylcholines

    Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfers the fatty acid to cholesterol.

     Lysophosphatidylcholines Chemical Structure
  90. GC44112 Mabuterol Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR). Mabuterol Chemical Structure
  91. GC47597 Manidipine-d4 An internal standard for the quantification of manidipine Manidipine-d4 Chemical Structure
  92. GC41595 Matairesinol Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets. Matairesinol Chemical Structure
  93. GC49486 Meglutol-d3 An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  94. GC45508 MEGX (hydrochloride)   MEGX (hydrochloride) Chemical Structure
  95. GC40078 Memantine-d6 (hydrochloride) Memantine-d6 is intended for use as an internal standard for the quantification of memantine by GC- or LC-MS. Memantine-d6 (hydrochloride) Chemical Structure
  96. GC44155 Menaquinone 9

    Menaquinone 9 (MK-9) is a vitamin K2 analog that has been found in various bacteria, including E.

     Menaquinone 9 Chemical Structure
  97. GC44170 Metaraminol (tartrate) Metaraminol is a vasoconstrictor. Metaraminol (tartrate) Chemical Structure
  98. GC47645 Methidathion An organophosphate insecticide Methidathion Chemical Structure
  99. GC48661 Methylatropine (nitrate) A muscarinic acetylcholine receptor antagonist Methylatropine (nitrate) Chemical Structure
  100. GC44180 Methylcarbamyl PAF C-16 Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. Methylcarbamyl PAF C-16 Chemical Structure
  101. GC41639 Methyldopate Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension. Methyldopate Chemical Structure

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