Metabolism
- Sterol Biosynthesis(26)
- PPAR(183)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(6)
- Aminopeptidase(7)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(56)
- CETP(9)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(22)
- Dehydrogenase(132)
- DHFR(6)
- DGAT(8)
- Dopamine β-hydroxylase(10)
- Enolase(11)
- FAAH(34)
- Factor Xa(41)
- Ferroptosis(159)
- Folate Analogue(2)
- Glucokinase(17)
- HLE(0)
- HMG-CoA Reductase(34)
- HSP(59)
- IDO(45)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(120)
- PDE(223)
- Phospholipase(113)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(16)
- SGLT(26)
- TPH(4)
- Transferase(177)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(92)
- Pyruvate kinase(8)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Products for Metabolism
- Cat.No. Nom du produit Informations
-
GC18575
2-hydroxy Tricosanoic Acid methyl ester
Methyl 2-hydroxytricosanoate
2-hydroxy Tricosanoic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in ripe and unripe strawberry homogenates, Pseudosuberites and S. -
GC49840
2-Methylbutyrylglycine
2-MBG, N-sec-Valerylglycine
A metabolite of isoleucine -
GC48617
2-Methylhexacosane
2-Me-C26
An insect pheromone -
GC52170
2-Nitroamino-2-imidazoline
NSC 25961, NSC 65424, NSC 91792
-
GC42189
2-oxo Clopidogrel
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
-
GC12262
2-Phenyl-2-(1-piperidinyl)propane
1-(α,α-dimethylbenzyl)-Piperidine,PPP
Le 2-phényl-2-(1-pipéridinyl)propane est un inhibiteur sélectif et réversible du CYP2B6 humain avec une IC50 de 5,1 μM et un Ki de 5,6. -
GC42193
2-Thenoyltrifluoroacetone
NSC 66544, NSC 405702, NSC 405703, NSC 405704, NSC 405705, NSC 405706, TTFA
La 2-thénoyltrifluoroacétone est un agent chélateur. -
GC52083
21-Deoxycortisone
21-Desoxycortisone, NSC 38722
A corticosteroid metabolite of 11-keto progesterone -
GC40968
21-hydroxy Eplerenone
21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.
-
GC18270
22(S)-hydroxy Cholesterol
22β-hydroxy Cholesterol
A synthetic oxysterol and LXR modulator -
GC41614
24-dehydro Cholesterol
Desmosterol
Le 24-déhydrocholestérol est une molécule similaire au cholestérol.
-
GC46243
24-dehydro Cholesterol-d6
Desmosterol-d6
An internal standard for the quantification of 24-dehydro cholesterol -
GC49365
25-Desacetyl Rifampicin
Desacetylrifampicin
A major active metabolite of rifampicin -
GC18490
2α-Mannobiose
2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.
-
GC49658
3β-Cholic Acid
3β-Epicholic Acid
A bile acid -
GC46068
3β-OH-7-Oxocholenic Acid
3β-hydroxy-7-oxo-5-Cholenoic Acid, 3β-hydroxy-7-Oxochol-5-enoic Acid
A bile acid -
GC33059
3α-Aminocholestane
3AC
Le 3α-Aminocholestane est un inhibiteur sélectif de l'inositol-5′-phosphatase 1 (SHIP1) contenant un domaine SH2 avec une IC50 d'environ 2,5 μM. -
GC41480
3'-hydroxy Lidocaine
m-hydroxy Lidocaine, meta-hydroxy Lidocaine
3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. -
GC42312
3'-Sialyllactose (sodium salt)
3'-N-Acetylneuraminyl-D-lactose
3'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 3 position. -
GC52109
3,3′-Dipropylthiadicarbocyanine (iodide)
DiS-C3-(5), DiSC3(5)
3,3ò-Dipropylthiadicarbocyanine (iodure) est une sonde fluorescente souvent utilisée comme colorant traceur pour évaluer le potentiel de la membrane mitochondriale. -
GC46030
3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)
An ENPP1 inhibitor
-
GC42204
3,4,6-Tri-O-benzyl-β-D-Mannopyranose 1,2-(methyl orthoacetate)
3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(methyl orthoacetate) is a synthetic intermediate used in glycosylation reactions.
-
GC12624
3,4-DAA
synthetic derivative of the tryptophan metabolite anthranilic acid
-
GC49427
3,5-Diiodo-L-thyronine
3,5-Diiodothyronine, NSC 90469, 3,5-T2
La 3,5-Diiodo-L-thyronine est un métabolite endogène. -
GC18205
3,5-Diiodothyroacetic Acid
Diac, NSC 90463, T2A, TA2
3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine. -
GC49169
3,8’-Biapigenin
I3,II8-Biapigenin, 3,8\-Biapigenin
3,8’-Biapigenine est une biflavone dans Hypericum perforatum L. -
GC52324
3-(3-Hydroxyphenyl)propionic Acid sulfate
3-HPPA sulfate
A metabolite of certain phenols and glycosides -
GC42198
3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
γ-Hydroxybaclofen
An inactive metabolite of baclofen -
GC14282
3-acetyl-11-keto-β-Boswellic Acid
3-O-acetyl-11-keto-β-Boswellic acid,AKBA
L'acide 3-acétyl-11-céto-β-boswellique (acétyl-11-céto-β-acide boswellique) est un composé triterpénoÏde actif issu de l'extrait de boswellia serrate et un nouvel activateur Nrf2. -
GC46583
3-Amino-2,6-Piperidinedione
α-Aminoglutarimide, 3-Aminoglutarimide, Glutamimide
An active metabolite of (±)-thalidomide -
GC52129
3-Amino-5-hydroxybenzoic Acid
AHBA
-
GC10554
3-Cyano-7-ethoxycoumarin
La 3-cyano-7-éthoxycoumarine est un substrat fluorogène du cytochrome P-450 qui génère un produit fluorescent bleu lors du clivage enzymatique.
-
GC14713
3-Deazaadenosine
c3Ado, deazaAdo, 3-DZA
3-Deazaadenosine (chlorhydrate) est un inhibiteur de l'hydrolyse de S-adénosylhomocystéine, avec un Ki de 3. -
GC42261
3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid
Deaminoneuraminic acid
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors.
-
GC49180
3-epi-25-hydroxy Vitamin D3
3-epi-25(OH)D3, 3-epi-25-hydroxy Cholecalciferol
The C-3 epimer of 25-hydroxy vitamin D3 -
GC18462
3-Formylsalicylic Acid
NSC 55753
3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone. -
GC41632
3-hydroxy Carbofuran
3-hydroxy Carbofuran is an active metabolite of carbofuran, which is an insecticide that inhibits acetylcholinesterase in mammals and insects.
-
GC42274
3-hydroxy Darifenacin
UK 148993
3-hydroxy Darifenacin is a metabolite of darifenacin. -
GC42275
3-hydroxy Desloratidine
SCH 45581
3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor. -
GC41565
3-hydroxy Medetomidine
3-OH Medetomidine, Medetomidine metabolite MIII
3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine. -
GC42289
3-hydroxy Tridecanoic Acid methyl ester
Methyl 3-hydroxytridecanoate
3-hydroxy Tridecanoic acid methyl ester is a hydroxylated fatty acid methyl ester and major fatty acid component of A. -
GC42292
3-Hydroxypropionic Acid (sodium salt)
Sodium β-hydroxypropionate
3-Hydroxypropionic acid is a building block in the synthesis of a variety of compounds with industrial applications, including acrylic acid, acrylamide, and 1,3-propanediol. -
GC48457
3-keto Fusidic Acid
3-keto FA, 3-Oxofusidic Acid
An active metabolite of fusidic acid -
GC49149
3-Methylglutaconic Acid
β-Methylglutaconic Acid, 3-MGA, 3-MGC Acid, NSC 249232
A branched-chain organic acid -
GC65595
3-Nitrocoumarin
3-Nitrocoumarine (3-NC) est un inhibiteur puissant et sélectif de la Phospholipase C-gamma (PLC-gamma).
-
GC17394
3-Nitropropionic acid
β-Nitropropionic Acid, 3-NP, NSC 64266
L'acide 3-nitropropionique (β-acide nitropropionique) est un inhibiteur irréversible de la succinate déshydrogénase. -
GC42307
3-O-methyl-L-DOPA (hydrate)
3-O-methyl-3,4-Dihydroxyphenylalanine, 3-methoxy DOPA, 3-OMD
3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase. -
GC42308
3-O-methyl-N-acetyl-D-Glucosamine
3-O-methylGlcNAc
La 3-O-méthyl-N-acétyl-D-glucosamine est un puissant inhibiteur de la N-acétylglucosamine kinase. -
GC60024
3-O-Methylquercetin
NSC 154016, Quercetin 3-methyl ether
La 3-O-méthylquercétine (3-MQ), un constituant principal de Rhamnus nakaharai, inhibe l'AMPc total et la GMPc-phosphodiestérase (PDE) de la trachée de cobaye. -
GC40692
3-Propylxanthine
D 4028, Enprofylline
La 3-propylxanthine agit comme un antagoniste sélectif et compétitif des récepteurs A2B avec le Ki de 7 μM. -
GC12289
3-Thiatetradecanoic Acid
3-TDA
activator of PPAR -
GC52149
306-O12B
Un lipidoïde cationique ionisable
-
GC46678
4β-hydroxy Cholesterol-d7
An internal standard for the quantification of 4β-hydroxy cholesterol
-
GC49367
4’-hydroxy Atomoxetine Glucuronide (hydrate)
A metabolite of atomoxetine
-
GC49252
4’-hydroxy Trazodone
A metabolite of trazodone
-
GC18527
4'-hydroxy Flurbiprofen
A major active metabolite of flurbiprofen
-
GC33071
4'-Methylchrysoeriol
Le 4'-méthylchrysoeriol est un puissant inhibiteur des enzymes du cytochrome P450, avec une IC50 de 19 nM pour l'EROD dépendant du P450 1B1 humain.
-
GC41582
4(Z),7(Z)-Decadienoic Acid
4(Z),7(Z)-Decadienoic acid is a polyunsaturated fatty acid (PUFA).
-
GC42326
4,6-O-Benzylidene-D-glucose
4,6-O-Benzylidene-D-glucopyranose
4,6-O-Benzylidene-D-glucose is a useful intermediate for the synthesis of carbohydrates. -
GC17159
4-(n-nonyl) Benzeneboronic Acid
L'acide 4-(n-nonyl) benzèneboronique (composé 13) est un puissant double inhibiteur FAAH et MAGL avec des valeurs IC50 de 9,1 nM et 7,9 μM, respectivement.
-
GC65517
4-(Trifluoromethyl)umbelliferone
La 4-(trifluorométhyl)umbelliférone est un substrat de sonde fluorescente pour les enzymes du cytochrome hépatique P450 du rat .
-
GC49337
4-Acetamidobenzenesulfonamide
APAS, N-Acetyl p-Aminobenzene Sulfonamide, N4-Acetyl Sulfanilamide, N-Acetylsulfanilamide, NSC 217, NSC 406839
A metabolite of asulam and sulfanilamide -
GC46069
4-Amino-5-(bromomethyl)-2-methylpyrimidine (hydrobromide)
La 4-amino-5-(bromométhyl)-2-méthylpyrimidine (bromhydrate) est un inhibiteur potentiel de la kinase du récepteur couplé aux protéines G (GRK).
-
GC42337
4-Aminobenzoic Acid (sodium salt)
PABA, p-Aminobenzoic Acid
4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi. -
GC49494
4-Aminobenzylphosphonic Acid
4-ABPA, NSC 12117
An alkaline phosphatase inhibitor -
GC18194
4-Epidoxycycline
4-ED
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline . -
GC18858
4-hydroxy Alternariol
4-hydroxy AOH, 4-OH AOH
4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism. -
GC42405
4-hydroxy Atorvastatin (calcium salt)
p-hydroxy Atorvastatin, para-hydroxy Atorvastatin
4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. -
GC18425
4-hydroxy Atorvastatin lactone
p-hydroxy Atorvastatin lactone, para-hydroxy Atorvastatin lactone
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
-
GC49575
4-hydroxy Omeprazole sulfide
4-hydroxy OMEP sulfide, 4-hydroxy OMP sulfide, 4-hydroxy OMZ sulfide
A metabolite of omeprazole -
GC40879
4-hydroxy Solifenacin N-oxide
4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .
-
GC42415
4-hydroxy Valsartan
CGP 71580, Valeryl 4-hydroxy Valsartan
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan. -
GC18417
4-hydroxy Xylazine
p-hydroxy Xylazine, para-hydroxy Xylazine
4-hydroxy Xylazine est un métabolite de la xylazine.
-
GC60519
4-Hydroxyderricin
La 4-hydroxyderricine, les principaux ingrédients actifs d'Angelica keiskei Koidzumi, est un puissant inhibiteur sélectif de la MAO-B (inhibiteurs de la monoamine oxydase) avec une IC50 de 3,43 μM.
-
GC42434
4-methyl-2-Oxovalerate (sodium salt)
2-Ketoisocaproate, α-Ketoisocaproate, 2-Ketoisocaproic Acid, KIC, 4-MOP, 2-Oxoisocaproic Acid, 4-methyl-2-Oxopentanoate, 4-methyl-2-Oxovalerate, 4-methyl-2-Oxovaleric Acid
4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. -
GC42445
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt)
4-MU β-D-galactopyranoside-6-sulfate, 4-Methylumbelliferyl Gal-6S, 4-MU-Gal-6S
Le 4-méthylumbelliferyl β-D-galactopyranoside-6-sulfate (sel de sodium) est un colorant fluorescent. -
GC42446
4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside
4-Methylumbelliferyl N,N'-diacetyl-β-chitobioside, 4-ΜU-(GlcNAc)2
4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside (4-μU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases. -
GC42442
4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt)
4-MU-α-GlcNS
4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sel de sodium) est un substrat fluorogène de l'héparine sulfamidase, est désulfuré en 4-MU-α-GlcNH2. -
GC40510
4-Methylumbelliferyl-α-D-Galactopyranoside
MU-α-Gal, 4-MU-α-Gal
Le 4-méthylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), un substrat de la α-galactosidase A (GLA), est un substrat bleu pro-fluorogénique. -
GC42449
4-Methylumbelliferyl-α-L-Iduronide (free acid)
4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid, 4-MU-α-IdoA, MU-α-IdoA
4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. -
GC49114
4-Methylumbelliferyl-β-D-Galactoside
4-Methylumbelliferyl-β-D-Galactopyranoside
Le 4-méthylumbelliferyl-β-D-galactoside est un substrat fluorescent pour la β-galactosidase qui, lorsqu'il est clivé, produit un fluorophore de coumarine fluorescent bleu soluble dans l'eau qui peut être détecté À l'aide d'un fluoroenzymeter ou d'un fluoromètre. -
GC42452
4-Methylumbelliferyl-β-D-N,N',N''-Triacetylchitotrioside
MUF-triNAG
4-Méthylumbelliféryl-β-D-N,N',N''-triacétylchitotrioside est un substrat fluorogène pour les chitinases et les chitotriosidases.
-
GC11870
4-Methylumbelliferyl-β-D-Glucopyranoside
4-MU-GLU;4-MU-β-Gluc;4-MUG;MU-GLU
Le 4-méthylumbelliferyl-β-D-glucopyranoside, un β-D-glucoside, est un substrat fluorogène pour la β-glucosidase, utilisé pour doser l'activité de la β-glucosidase. -
GC52117
4-Nitrophenyl α-D-Glucopyranoside
p-Nitrophenyl α-D-Glucopyranoside, pNPG, para-Nitrophenyl-α-D-glucopyranoside
A colorimetric α-glucosidase substrate -
GC42462
4-Nitrophenyl β-D-Cellotrioside
p-Nitrophenyl β-D-Cellotrioside
4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate for endoglucanases and cellobiohydrolases. -
GC18209
4-Nitrophenyl β-D-Cellotetraoside
p-Nitrophenyl β-D-Cellotetraoside
4-Nitrophenyl β-D-cellotetraoside is small molecule cellulose mimic that consists of a tetramer of D-glucose units joined by β-1-4-glycosidic bonds. -
GC42463
4-Nitrophenyl-N-acetyl-α-D-galactosaminide
pNP-GlcNAc
N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin. -
GC45841
4-Nitrophenyl-N-acetyl-β-D-glucosaminide
GlcNAc-PNP, p-Nitrophenyl-N-acetyl-β-D-glucosaminide
A chromogenic substrate for N-acetyl-β-glucosaminidase -
GC35143
4-O-Methyl honokiol
NSC 293101, 4-Methoxyhonokiol
Le 4-O-méthyl honokiol est un néolignan naturel isolé de Magnolia officinalis, agit comme un agoniste PPARγ et inhibe l'activité NF-κB, utilisé pour la recherche sur le cancer et l'inflammation. -
GC49127
4-oxo Cyclophosphamide
4-keto CP, 4-keto Cyclophosphamide, NSC 139488, 4-oxo CP
An inactive metabolite of cyclophosphamide -
GC41530
4-oxo Docosahexaenoic Acid
4-oxo DHA
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. -
GC49244
4-oxo Isotretinoin
Ro 22-6595
An active metabolite of isotretinoin -
GC11731
4-phenyl-1,2,3-Thiadiazole
NSC 111906
selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1) -
GC11758
4-phenyl-5-methyl-1,2,3-Thiadiazole
NSC 358739
CYP2B4 and CYP2E1 inhibitor -
GC10762
4β-hydroxy Cholesterol
An endogenous marker for CYP3A4/5 activity
-
GC48843
5α-Androst-16-en-3α-ol
Androstenol, E 281, NSC 71076
A pheromone with diverse biological activities -
GC49542
5α-Androstan-3β-ol
NSC 50887
A steroidal androgen -
GC49862
5α-Cholanic Acid-3,6-dione
NSC 18165
A secondary bile acid -
GC41399
5α-dihydro Levonorgestrel
5α-DHLNG
5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel. -
GC40693
5α-hydroxy-6-keto Cholesterol
6Oxo3,5diol, Cholestane6oxo3β,5αdiol
5α-hydroxy-6-céto Le cholestérol est le principal métabolite de β-époxyde (5α,6β-époxycholestérol) lors de l'exposition directe À l'ozone de cellules épithéliales bronchiques humaines intactes cultivées (16-HBE).