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15(S)-Fluprostenol

カタログ番号GC40283

(+)-15(R)-フルプロステノールイソプロピルエステルは、角膜内のエステラーゼ酵素活性によって変換され、対応する遊離酸を生成するプロドラッグ(トラボプロスト)です。

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15(S)-Fluprostenol 化学構造

Cas No.: 54276-24-3

サイズ 価格 在庫数 個数
1mg
$94.00
在庫あり
5mg
$425.00
在庫あり
10mg
$754.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

(+)-15(R)-Fluprostenol isopropyl ester is a prodrug (Travoprost) which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid. The free acid, (+)-15(R)-fluprostenol, is a potent FP receptor agonist. The 15(R)-epimers of most prostaglandins are about 100 times less potent than the natural, 15(S)-isomers. However, the neighboring phenoxy group at C-16 reverses the absolute configuration at C-15 in the fluprostenol series; hence, 15(S)-fluprostenol is less active as an FP agonist than 15(R)-fluprostenol. The biology of 15(S)-fluprostenol has not been widely studied.

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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