3-Iodothyronamine (hydrochloride) (Synonyms: T1AM) |
カタログ番号GC42294 |
3-ヨードチロナミンは、内因性のチロキシンの脱ヨード化と脱炭酸化によって生成されます。
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Cas No.: 788824-64-6
Sample solution is provided at 25 µL, 10mM.
3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and cardiac output. It has also been reported to function in controlling lipid and glucose utilization, hormonal secretion, and neuronal function, and has been considered for use in chemically-induced hibernation for medical purposes.
Average Rating: 5
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