3-O-Methylquercetin (Synonyms: NSC 154016, Quercetin 3-methyl ether) |
| カタログ番号GC60024 |
Rhamnus nakaharai の主成分である 3-O-メチルケルセチン (3-MQ) は、モルモット気管の総 cAMP および cGMP-ホスホジエステラーゼ (PDE) を阻害します。
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Cas No.: 1486-70-0
Sample solution is provided at 25 µL, 10mM.
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3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM, 86.9 μM, 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1].
[1]. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5.
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