5-SAHSA |
カタログ番号GC42567 |
分岐脂肪酸エステルのヒドロキシ脂肪酸(FAHFA)は、断食や高脂肪摂取によって調節され、インスリン感受性と関連している新しく同定された内因性リピッドです。
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Sample solution is provided at 25 µL, 10mM.
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. 5-SAHSA is a FAHFA in which stearic acid is esterified to 5-hydroxy stearic acid. The levels of SAHSA are moderately elevated in the serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue. As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 5-SAHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.
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