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5(Z)-Dodecenoic Acid (Synonyms: C12:1 n-7, C12:1(5Z), cis-5-Dodecenoic Acid)

カタログ番号GC49499

5(Z)-ドデセン酸は、COX-I および COX-II に対する阻害活性を持つ内因性代謝産物です。

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5(Z)-Dodecenoic Acid 化学構造

Cas No.: 2430-94-6

サイズ 価格 在庫数 個数
10 mg
$33.00
在庫あり
25 mg
$75.00
在庫あり
50 mg
$119.00
在庫あり
100 mg
$188.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

5(Z)-Dodecenoic acid is a medium-chain unsaturated fatty acid. It is a precursor in the biosynthesis of the sex pheromone 5(Z)-dodecenal.1 5(Z)-Dodecenoic acid levels are increased in culture medium from MCF-7 breast cancer cells compared to KMST-6 fibroblasts.2 Levels of 5(Z)-dodecenoic acid are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting.3

1.Bestmann, H.J., Attygalle, A.B., Garbe, W., et al.Chemical structure and final steps of biosynthesis of the female sex pheromone of Gastropacha quercifolia (Lepidoptera: Lasiocampidae)Insect Biochem. Molec. Biol.23(7)793-799(1993) 2.Tanaka, M., Hsuan, C., Oeki, M., et al.Identification of characteristic compounds of moderate volatility in breast cancer cell linesPLoS One15(6)e0235442(2020) 3.Onkenhout, W., Venizelos, V., van der Poel, P.F.H., et al.Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disordersClin. Chem.41(10)1467-1474(1995)

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