AFP464 (Synonyms: NSC710464 free base) |
| カタログ番号GC33416 |
AFP464 (NSC710464 遊離塩基) は、アクティブな HIF-1α です。 IC50 が 0.25 μM の阻害剤であり、強力なアリール炭化水素受容体 (AhR) 活性化剤でもあります。
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Cas No.: 468719-52-0
Sample solution is provided at 25 µL, 10mM.
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AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator.
[1]. Terzuoli E1, Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1alpha expression in an AhR-independent fashion. Cancer Res. 2010 Sep 1;70(17):6837-48.
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