Ammonium iron(III) citrate |
| カタログ番号GC61895 |
非トランスフェリン結合鉄の生理学的形態であるクエン酸鉄（III）アンモニウム（クエン酸第二鉄アンモニウム）は、細胞内鉄過負荷を誘発してフェロトーシスを引き起こします。クエン酸鉄(III)アンモニウムは、タンパク質産生を増強することができます。
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Cas No.: 1185-57-5
Sample solution is provided at 25 µL, 10mM.
Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2].
Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter[1]. Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L[2].
References:
[1]. Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.
[2]. Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625.
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