Ammonium iron(III) citrate |
| Catalog No.GC61895 |
비트랜스페린 결합 철의 생리학적 형태인 구연산 암모늄 철(III)은 세포 내 철 과부하를 유도하여 페로프토시스를 유발합니다. 구연산 암모늄 철(III)은 단백질 생산을 향상시킬 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1185-57-5
Sample solution is provided at 25 µL, 10mM.
Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis[1]. Ammonium iron(III) citrate can enhance protein production[2].
Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter[1]. Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L[2].
References:
[1]. Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.
[2]. Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625.
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