Arachidonic Acid (sodium salt) (Synonyms: Sodium Arachidonate) |
| カタログ番号GC42833 |
多価不飽和脂肪酸（PUFA）は、十分な量が食事に含まれていない場合に特定の欠乏症候群を示す必須栄養素です。
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Cas No.: 6610-25-9
Sample solution is provided at 25 µL, 10mM.
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Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet.[1][2] Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways [3]. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signalling and inflammation.[4]
Reference:
[1]. Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. American Journal of Clinical Nutrition 54, 438-463 (1991).
[2]. Holman, R.T. Control of polyunsaturated acids in tissue lipids. J. Am. Coll. Nutr. 5(2), 183-211 (1986).
[3]. Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim. Biophys. Acta. 1300(3), 187-196 (1996).
[4]. Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels. Trends Biochem. Sci. 15(10), 365-366 (1990).
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