Arachidonic Acid (sodium salt) (Synonyms: Sodium Arachidonate) |
| Katalog-Nr.GC42833 |
Polyungesättigte Fettsäuren (PUFAs) sind essentielle Nährstoffe, die bei unzureichender Aufnahme in der Ernährung zu deutlichen Mangelerscheinungen führen können.
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Cas No.: 6610-25-9
Sample solution is provided at 25 µL, 10mM.
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Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet.[1][2] Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways [3]. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signalling and inflammation.[4]
Reference:
[1]. Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. American Journal of Clinical Nutrition 54, 438-463 (1991).
[2]. Holman, R.T. Control of polyunsaturated acids in tissue lipids. J. Am. Coll. Nutr. 5(2), 183-211 (1986).
[3]. Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim. Biophys. Acta. 1300(3), 187-196 (1996).
[4]. Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels. Trends Biochem. Sci. 15(10), 365-366 (1990).
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