Bisindolylmaleimide X (hydrochloride) (Synonyms: BIM X, Ro 31-8425) |
| カタログ番号GC18354 |
ビスインドリルマレイミド X (塩酸塩) (BIM-X 塩酸塩) は、強力で選択的なプロテインキナーゼ C (PKC) 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 145317-11-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Bisindolylmaleimide X is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 15 nM, rat brain PKC). It has been shown to inhibit PKCα, βI, βII, γ, and ε with IC50 values of 8, 8, 14, 13, and 39 nM, respectively. It has also been identified as an inhibitor of Cdk2 (IC50 = 200 nM) and GSK3α/β. This compound has been used to activate mesenchymal stem cells, increase the surface expression of homing ligands that bind to intercellular adhesion molecule 1, and target delivery of these cells to sites of inflammation.
Review for Bisindolylmaleimide X (hydrochloride)
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
Review for Bisindolylmaleimide X (hydrochloride)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *