Mc-VC-PAB-SN38 |
カタログ番号GC61036 |
Mc-VC-PAB-SN38 は、切断可能な ADC リンカー (Mc-VC-PAB) と DNA トポイソメラーゼ I 阻害剤 (SN38) で構成されています。 Mc-VC-PAB-SN38 は、抗体薬物複合体 (ADC) の合成に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1801838-28-7
Sample solution is provided at 25 µL, 10mM.
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Average Rating: 5
(Based on Reviews and 9 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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