Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin) |
| カタログ番号GC30816 |
Tyr-Gly-Gly-Phe-Met-OH (Met-エンケファリン) は、オピオイド受容体への結合を介してヒトの免疫機能を調節し、腫瘍の成長を阻害します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58569-55-4
Sample solution is provided at 25 µL, 10mM.
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Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1].
[1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.
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