RIP2 kinase inhibitor 2 |
| カタログ番号GC32860 |
RIP2 キナーゼ阻害剤 2 は、特許 WO/2014043437 A1、化合物例 9 から抽出された受容体相互作用タンパク質 2 (RIP2) キナーゼ阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1581270-11-2
Sample solution is provided at 25 µL, 10mM.
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RIP2 kinase inhibitor 2 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9.
RIP2 kinase inhibitor 2 is a novel prodrug of a quinazolyl amine that inhibits RIP2 kinase. Receptor interacting protein-2 (RIP2) kinase is a TKL family serine/threonine protein kinase involved in innate immune signaling. Following activation, RIP2 kinase associates with NODI or NOD2 and appears to function principally as a molecular scaffold to bring together other kinases (TAK1, Ικκα/β/γ) involved in NF-κβ and mitogen-activated protein kinase activation[1].
[1]. Linda N. Casillas, et al. Amino-quinolines as kinase inhibitors. PCT Int. Appl. (2014), WO 2014043437 A1 20140320.
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