Cefminox sodium |
| カタログ番号GC61805 |
セフミノックスナトリウム (MT-141) は半合成セファマイシンであり、幅広い抗菌活性を示します 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 75498-96-3
Sample solution is provided at 25 µL, 10mM.
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Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity[1]. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension[2].
[1]. Inouye S, et al. In vitro and in vivo antibacterial activities of MT-141, a new semisynthetic cephamycin, compared with those of five cephalosporins. Antimicrob Agents Chemother. 1984 Nov;26(5):722-9. [2]. Xia J, et al. Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats. Front Pharmacol. 2018 Feb 23;9:134.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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