CTTHWGFTLC, CYCLIC TFA |
| カタログ番号GC60114 |
CTTHWGFTLC、CYCLIC TFA は、マトリックスメタロプロテイナーゼ MMP-2 および MMP-9 の環状ペプチド阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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CTTHWGFTLC, CYCLIC TFA is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9. The IC50 value for MMP-9 is ~8 μM[1].
CTTHWGFTLC, CYCLIC TFA inhibits endothelial and tumor cell migration in vitro[1].
CTTHWGFTLC, CYCLIC TFA inhibits tumor progression in vivo, in mouse models[1].
[1]. Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.
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