DC1-SMe |
| カタログ番号GC34190 |
ＤＣ１誘導体であるＤＣ１Ｓｍｅは、Ｒａｍｏｓ、Ｎａｍａｌｗａ、ＨＬ６０／ｓおよびＣＯＬＯ２０５癌細胞に対してそれぞれ２２ｐＭ、１０ｐＭ、３２ｐＭおよび２５０ｐＭのＩＣ５０値を示す。副溝結合 DNA アルキル化剤 CC-1065 の類似体である DC1 は、ADC 細胞毒素です。 DC1 は、がんの標的治療のための抗体薬物コンジュゲートの合成に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 501666-85-9
Sample solution is provided at 25 µL, 10mM.
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DC1-Sme is an antibody conjugate of phosphate prodrug of cytotoxic DNA alkylators for the targeted treatment of cancer.
[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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