Dimethindene maleate |
| カタログ番号GC66445 |
マレイン酸ジメチンデンは、抗ヒスタミン効果を持つ選択的ヒスタミン H1 拮抗薬です。マレイン酸ジメチンデンは、過敏症反応の研究に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3614-69-5
Sample solution is provided at 25 µL, 10mM.
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Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions[1][2][3].
Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K?? currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM[2].
Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K?? currents with an IC50 value of 49 μM[2].
Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice[1].
| Animal Model: | C57BL/6 mice with wound healing[1] |
| Dosage: | 0.25 mg |
| Administration: | Intraperitoneal injection; 0.25 mg once |
| Result: | Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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