Dimethindene maleate |
Katalog-Nr.GC66445 |
Dimethindenmaleat ist ein selektiver Histamin-H1-Antagonist mit antihistaminischer Wirkung. Dimethindenmaleat kann zur Erforschung von Überempfindlichkeitsreaktionen eingesetzt werden.
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Cas No.: 3614-69-5
Sample solution is provided at 25 µL, 10mM.
Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions[1][2][3].
Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K?? currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM[2].
Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K?? currents with an IC50 value of 49 μM[2].
Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice[1].
Animal Model: | C57BL/6 mice with wound healing[1] |
Dosage: | 0.25 mg |
Administration: | Intraperitoneal injection; 0.25 mg once |
Result: | Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing. |
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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