Amyloid β-Protein (17-40) |
カタログ番号GA20742 |
APPはα-シークレターゼとγ-シークレターゼによる切断(すなわち非アミロイド原性経路)によって、p3ペプチド、つまりAβ17-40およびAβ17-42の混合物が生成されます。 p3はAD脳で観察される拡散性斑点およびダウン症候群の影響を受けた人々の前アミロイド斑点の主要成分です。
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Cas No.: 156790-69-1
Sample solution is provided at 25 µL, 10mM.
Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affecte
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