Phthalic acid mono-2-ethylhexyl ester (Synonyms: MEHP, Mono-2-ethylhexyl Phthalate) |
| カタログ番号GC36902 |
フタル酸モノ-2-エチルヘキシルエステル (MEHP) は、CYP17 の 17, 20 リアーゼ活性を阻害するフタル酸ジエチルヘキシル (DEHP) の主要な生物活性代謝物です 。
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Cas No.: 4376-20-9
Sample solution is provided at 25 µL, 10mM.
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Phthalic acid mono-2-ethylhexyl ester (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP), which inhibits the 17, 20 lyase activity of CYP17[1].
[1]. Bai J, et al. Mono-2-ethylhexyl phthalate induces the expression of genes involved in fatty acid synthesis in HepG2 cells. Environ Toxicol Pharmacol. 2019 Jul;69:104-111. [2]. ChauvignÉ F, et al. Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis. PLoS One. 2011;6(11):e27172.
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