Zaurategrast ethyl ester |
| カタログ番号GC37961 |
CT7758のエチルエステルプロドラッグであるザウラテグラストエチルエステル（CDP323）は、炎症性疾患および自己免疫疾患の治療に使用されるα4β1/α4β7インテグリン拮抗薬です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 455264-30-9
Sample solution is provided at 25 µL, 10mM.
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Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. α4β1/α4β7 integrin[1]
Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].
[1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91. [2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases• Drug Discov Today. 2007 Jul;12(13-14):569-76.
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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