ZED-1227 |
カタログ番号GC37963 |
ZED-1227 は、特定の経口活性トランスグルタミナーゼ 2 (TG2) 阻害剤であり、IC50 は 45 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1542132-88-6
Sample solution is provided at 25 µL, 10mM.
ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1]. TG2[1]
[1]. Manu Encalada, et al. The Oral Transglutaminase 2 (TG2) Inhibitor Zed1227 Blocks TG2 Activity in a Mouse Model of Intestinal Inflammation. Gastroenterology. 154(6):S-490.
Average Rating: 5
(Based on Reviews and 38 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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