Ilimaquinone |
| カタログ番号GC18545 |
海綿の代謝産物であるイリマキノンは、GADD153 を介した経路を介して抗がん作用を示します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 71678-03-0
Sample solution is provided at 25 µL, 10mM.
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Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. In mammalian cells, 25 uM ilimaquinone reversibly induces vesiculation of Golgi membranes, blocking the secretory pathway. It inhibits the conversion of S-adenosylhomocysteine (SAH) to homocysteine by SAH hydrolase (IC50 = 40 uM). Ilimaquinone also inhibits DNA polymerase β and dual specificity phosphatase Cdc25B (IC50 = 45.2 and 92 uM, respectively) and, at 10 uM, activates gene expression through hypoxia-inducible factor-1.
Review for Ilimaquinone
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
Review for Ilimaquinone
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