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KRAS G12C inhibitor 5

カタログ番号GC34162

KRAS G12C 阻害剤 5 は、特許 WO2017201161A1、化合物例 147 から抽出された KRas G12C 阻害剤です。

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KRAS G12C inhibitor 5 化学構造

Cas No.: 2158297-63-1

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Sample solution is provided at 25 µL, 10mM.

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KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].

[1]. John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.

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