L-681,217 |
カタログ番号GC44020 |
L-681,217は、元々S.から分離された抗生物質です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
L-681,217 is an antibiotic originally isolated from S. cattleya. It is active against Gram positive and Gram negative bacteria when used at a concentration of 255 µg/ml. L-681,217 inhibits bacterial protein synthesis at the elongation stage, completely inhibiting poly(U)-dependent poly(Phe) synthesis (EC50 = 0.4 µM) and increasing elongation factor Tu (EF-Tu)-associated GTPase activity in E. coli (EC50 = 6 µM). It does not inhibit poly(U)-dependent poly(Phe) synthesis in S. aureus (EC50 = >1,000 µM).
Average Rating: 5
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