MMP-9 Inhibitor I (Synonyms: Matrix Metalloproteinase-9 Inhibitor I) |
| カタログ番号GC44237 |
MMP-9阻害剤Iは、マトリックスメタロプロテアーゼ-9（MMP-9）の阻害剤であり、MMP-1およびMMP-13に対して選択的です（それぞれIC50が5、1,050、および113 nM）。
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Cas No.: 206549-55-5
Sample solution is provided at 25 µL, 10mM.
MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 µM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 µM.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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