Mn(III)TMPyP |
カタログ番号GC44239 |
Mn(III)TMPyPは、スーパーオキシドジスムターゼ(SOD)ミメティックおよびペルオキシニトライト分解触媒として機能するマンガン-ポルフィリンです。
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Sample solution is provided at 25 µL, 10mM.
Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, respectively. Mn(III)TMPyP protected and enhanced the growth of SOD null E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 µM.
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