BI-4464 |
| カタログ番号GC34488 |
BI-4464 は、PTK2/FAK の高度に選択的な ATP 競合阻害剤であり、IC50 は 17 nM です。 PROTACのPTK2リガンド。
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Cas No.: 1227948-02-8
Sample solution is provided at 25 µL, 10mM.
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BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1]. IC50: 17 nM (PTK2/FAK)[1].
[1]. Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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