PEO-IAA (2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid) |
| カタログ番号GC30168 |
PEO-IAA (2-(1H-インドール-3-イル)-4-オキソ-4-フェニル-酪酸) は、インドール-3-酢酸 (IAA) 拮抗薬です。
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Cas No.: 6266-66-6
Sample solution is provided at 25 µL, 10mM.
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PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
PEO-IAA is also an α-alkyl-IAA, and shows more potent anti-auxin activity in auxin-responsive gene expression and in the cell division and elongation pathway that is mediated via SCFTIR1/AFBs. PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature. PEO-IAA blocks the auxin response in Arabidopsis, rice, moss and maize[1].
[1]. Nishimura T, et al. Differential downward stream of auxin synthesized at the tip has a key role in gravitropic curvature via TIR1/AFBs-mediated auxin signaling pathways. Plant Cell Physiol. 2009 Nov;50(11):1874-85.
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