PROTAC IRAK4 degrader-1 |
カタログ番号GC62197 |
PROTAC IRAK4 デグレーダー 1 は、特許 US20190192668A1 化合物 I-210 から抽出されたセレブロン ベースの PROTAC インターロイキン 1 受容体関連キナーゼ 4 (IRAK4) デグレーダーであり、0.01、0.1、およびそれぞれOCI-LY-10細胞で1μM。
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Cas No.: 2360533-90-8
Sample solution is provided at 25 µL, 10mM.
PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].
[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
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