PTP Inhibitor III (Synonyms: α-Bromo-4-(carboxymethoxy)acetophenone, Protein Tyrosine Phosphatase Inhibitor III) |
| カタログ番号GC44774 |
PTP阻害剤IIIは、タンパク質チロシンリン酸化酵素（PTP）の光可逆的共有結合阻害剤として機能するα-ハロアセトフェノン誘導体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 29936-81-0
Sample solution is provided at 25 µL, 10mM.
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PTP Inhibitor III is an α-haloacetophenone derivative that acts as a photoreversible covalent inhibitor of protein tyrosine phosphatases (PTPs). It binds the catalytic domain of SHP-1 (Ki = 184 µM) and covalently reacts with free thiols, a reaction that is reversible with irradiation (350 nm). PTP Inhibitor III is cell permeable and inhibits a broad range of PTPs.
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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