Quinaldopeptin |
| カタログ番号GC44798 |
ストレプトバーティシリウム アルバム株の培養から分離されたキナルドペプチンは、グラム陽性菌および嫌気性菌に対して非常に活性が高く、培養された B16 メラノーマ細胞に対して強い細胞毒性を示します 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130743-07-6
Sample solution is provided at 25 µL, 10mM.
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Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 µg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 µg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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