Quinaldopeptin |
| Catalog No.GC44798 |
Streptoverticillium album 균주의 배양액에서 분리한 quinomycin계 항생제인 Quinaldopeptin은 그람양성균과 혐기성균에 대한 활성이 높고 배양된 B16 흑색종 세포에 대한 세포독성이 강하다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130743-07-6
Sample solution is provided at 25 µL, 10mM.
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Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 µg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 µg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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