Z-VRPR-FMK (trifluoroacetate salt) (Synonyms: Z-Val-Arg-Pro-DL-Arg-FMK) |
カタログ番号GC45192 |
Z-VRPR-FMKは、粘膜関連リンパ組織リンパ腫転座タンパク質1(MALT1)の選択的で不可逆的な阻害剤であり、BCL10を標的とするエンドペプチダーゼであり、12.5〜75μMにおいてリンパ球のNF-κB活性化を低下させます。
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Sample solution is provided at 25 µL, 10mM.
Z-VRPR-FMK is a selective, irreversible inhibitor of the paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), an endopeptidase that targets BCL10 and reduces NF-κB activation in lymphocytes at 12.5 to 75 µM. Other MALT1 substrates that may be affected by Z-VRPR-FMK are TNFAIP3 and CYLD.
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