BCI-215 |
| Catalog No.GC39160 |
BCI-215는 강력한 종양 세포 선택적 이중 특이성 MAPK 포스파타제(DUSP-MKP) 억제제입니다. BCI-215는 종양 세포에 대한 세포 독성이 있지만 정상 세포에는 없습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1245792-67-9
Sample solution is provided at 25 µL, 10mM.
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BCI-215 is a potent and tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells[1][2].
[1]. Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45. [2]. Kaltenmeier CT, et al. A Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity. J Pharmacol Exp Ther. 2017 Apr;361(1):39-50.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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