GW-406381 (Synonyms: GW406381X) |
Catalog No.GC36200 |
고선택성 시클로옥시게나제-2(COX-2) 억제제인 GW406381은 만성 수축 손상 후 쥐의 비복 신경에서 자발적인 이소성 분비물을 약화시킵니다.
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Cas No.: 221148-46-5
Sample solution is provided at 25 µL, 10mM.
GW406381, a highly selective cyclooxygenase-2 (COX-2) inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury[1][2]. COX-2
[1]. Zhao FY, et al. GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury. Pain. 2007 Mar;128(1-2):78-87. [2]. Boswell DJ, et al. Evaluation of GW406381 for treatment of osteoarthritis of the knee: two randomized, controlled studies. Medscape J Med. 2008;10(11):259.
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