JAK3 covalent inhibitor-1 |
| Catalog No.GC36365 |
JAK3 공유 억제제-1은 IC50이 11nM인 강력하고 선택적인 야누스 키나제 3(JAK3) 공유 억제제이며 다른 JAK에 비해 246배 선택성을 나타냅니다.
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Cas No.: 2300106-50-5
Sample solution is provided at 25 µL, 10mM.
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JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1]. JAK3|11 nM (IC50)
[1]. Casimiro-Garcia A, et al. Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J Med Chem. 2018 Dec 13;61(23):10665-10699.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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