>>Signaling Pathways>> Proteases>> Acyltransferase>>GOAT-IN-1

GOAT-IN-1

Catalog No.GC31080

GOAT-IN-1은 그렐린 O-아실트랜스퍼라제(GOAT)의 억제제로 비만, 당뇨병, 고지혈증, 대사성, 비알코올성 지방간, 지방간염, 근육감소증, 식욕 조절, 알코올/ 마약 의존, 알츠하이머병, 파킨슨병, 뇌혈관성 치매, 뇌졸증, 뇌경색, 심장병, 일종의 종양.

Products are for research use only. Not for human use. We do not sell to patients.

GOAT-IN-1 Chemical Structure

Cas No.: 1452473-54-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer's disease, Parkinson's disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.

The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM[1].

[1]. WO 2013125732.

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